Amazonas ([amaˈzonɐs] (listen)) is a state of Brazil, located in the North Region in the northwestern corner of the country. It is the largest Brazilian state by area and the 9th largest country subdivision in the world, and the largest in South America, being greater than the areas of Uruguay, Paraguay, and Chile combined. Mostly located in the Southern Hemisphere, it is the third largest country subdivision in the Southern Hemisphere after the Australian states of Western Australia and Queensland. Entirely in the Western Hemisphere, it is the fourth largest in the Western Hemisphere after Greenland, Nunavut and Alaska. It would be the sixteenth largest country in land area, slightly larger than Mongolia. Neighbouring states are (from the north clockwise) Roraima, Pará, Mato Grosso, Rondônia, and Acre. It also borders the nations of Peru, Colombia and Venezuela. This includes the Departments of Amazonas, Vaupés and Guainía in Colombia, as well as the Amazonas state in Venezuela, and the Loreto Region in Peru. Amazonas is named after the Amazon River, and was formerly part of the Spanish Empire's Viceroyalty of Peru, a region called Spanish Guyana. It was settled by the Portuguese moving northwest from Brazil in the early 18th century and incorporated into the Portuguese empire after the Treaty of Madrid in 1750. It became a state under the First Brazilian Republic in 1889. Most of the state is tropical jungle; cities are clustered along navigable waterways and are accessible only by boat or plane. The capital and largest city is Manaus, a modern city of 2.1 million inhabitants in the middle of the jungle on the Amazon River, 1,500 km upstream from the Atlantic Ocean. Nearly half the state's population lives in the city; the other large cities, Parintins, Manacapuru, Itacoatiara, Tefé, and Coari are also along the Amazon River in the eastern half of the state. From Wikipedia