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AI Blood Test ARTEMIS-DELFI Revolutionizes Pancreatic Cancer Treatment Monitoring

Johns Hopkins researchers validate non-invasive, early-response blood test in phase 2 trials, paving the way for improved patient outcomes and broader cancer applications.

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Overview

  • ARTEMIS-DELFI uses AI to analyze cfDNA fragmentation patterns, offering faster and more accurate therapeutic response monitoring for pancreatic cancer patients.
  • Validated in two phase 2 trials, CheckPAC and PACTO, the test outperformed conventional imaging and tumor-informed assays like WGMAF.
  • The test identifies treatment effectiveness as early as four weeks, enabling clinicians to adjust therapies swiftly through a 'fast-fail' approach.
  • Unlike tumor-informed methods, ARTEMIS-DELFI operates independently of tumor biopsies, making it more accessible and applicable to diverse patient populations.
  • Prospective studies are planned to assess its impact on patient survival and explore its use in monitoring other cancer types.