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AI test identifies which prostate cancer patients could halve their death risk with abiraterone

NHS England is reviewing its policy following research that shows the tool pinpoints the quarter of men whose five-year mortality drops from 17% to 9% with the drug

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Overview

  • The AI test developed by Artera and trialled by The Institute of Cancer Research and UCL analyses tumour biopsy images to detect biomarkers invisible to the human eye.
  • In a trial of over 1,000 men with high-risk non-metastatic prostate cancer, biomarker-positive patients saw their five-year death risk cut from 17% to 9% when given abiraterone.
  • The NHS in England currently does not fund abiraterone for this patient group, creating a regional disparity with Scotland and Wales where the drug is available.
  • With abiraterone priced at £77 per pack since its 2022 patent expiry, targeting treatment could be cost-effective for roughly 2,100 men annually.
  • Leading researchers and patient advocates are urging NHS England and the Department of Health and Social Care to expand funding now that the AI test can identify who benefits most.