Aspirin Shows Potential in Preventing Cancer Spread Through Immune Boost
New research reveals aspirin may hinder cancer metastasis by freeing immune T cells to attack migrating cancer cells.
- A University of Cambridge-led study discovered aspirin can block a platelet-derived molecule, thromboxane A2 (TXA2), which suppresses immune T cells' ability to fight metastasizing cancer cells.
- The research, published in *Nature*, highlights a newly uncovered pathway explaining aspirin's role in reducing cancer metastasis, a process responsible for 90% of cancer-related deaths.
- In experiments with mice, aspirin significantly reduced metastases, confirming its potential to prevent cancer spread by enhancing T cell activity.
- While promising, aspirin use carries risks such as gastrointestinal bleeding and requires careful evaluation by healthcare providers for individual patients.
- Ongoing clinical trials, including the Add-Aspirin trial, aim to determine the safety and efficacy of aspirin in preventing cancer recurrence in humans.