Overview
- Jose Altuve powered the Astros with two home runs and four RBIs, marking his 12th career multi-homer game.
- Jeremy Peña's two-run triple in the fourth inning not only extended Houston's lead but also marked his 500th career hit.
- Lance McCullers Jr. delivered his longest start of the season, striking out eight over 4 1/3 innings in his continued return from a two-year injury absence.
- Seattle's George Kirby struggled in his season debut, giving up five runs in 3 2/3 innings after recovering from shoulder inflammation.
- Mariners center fielder Julio Rodríguez was a late scratch from the lineup, with no immediate explanation provided, adding uncertainty to Seattle's roster moving forward.