Blocking IL-11 Protein Extends Mouse Lifespan by Nearly 25%

New research shows anti-inflammatory treatment reduces age-related diseases and frailty in mice, with potential implications for human health.

Researchers found that inhibiting IL-11 can extend mouse lifespan by 22.5% in males and 25% in females.
The treatment also reduced age-related diseases, improved muscle function, and decreased frailty in older mice.
IL-11 blocking therapies are currently in early-stage clinical trials for other conditions, offering a chance to study their effects on human aging.
Experts caution that translating these findings from mice to humans presents significant challenges and potential side effects.
The focus of anti-aging research is shifting towards improving healthspan, not just extending lifespan.