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Breakthrough Identifies Brain Pathway to Reduce Obesity Drug Side Effects

Researchers discover distinct neural circuits that can promote weight loss without causing nausea, potentially improving future treatments.

  • Scientists at Monell Chemical Senses Center found separate brain circuits for satiety and nausea in mice.
  • Current obesity drugs like Ozempic and Wegovy cause nausea, leading some users to stop treatment.
  • Targeting the nucleus tractus solitarius in the brain can trigger feelings of fullness without aversion.
  • The study suggests potential for developing obesity drugs with fewer side effects.
  • Findings were published in the journal Nature, highlighting a major step forward in obesity treatment.
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