First Pig Liver Transplant into Human Marks Major Medical Milestone

Chinese researchers successfully transplanted a gene-edited pig liver into a brain-dead patient, with the organ functioning for 10 days, demonstrating potential for future clinical applications.

The genetically modified pig liver, transplanted as an auxiliary organ, produced bile and maintained blood flow without signs of rejection during the 10-day trial.
The liver was sourced from a Bama miniature pig with six genetic modifications to reduce immune rejection and improve compatibility with humans.
The procedure was conducted ethically, with family consent and approval from medical authorities, and was terminated at the family's request.
This breakthrough, published in the journal Nature, highlights the potential of pig livers as temporary 'bridge' organs for patients awaiting human transplants.
Researchers plan further studies, including trials on living patients and complete liver replacements, while addressing long-term functionality and ethical considerations.

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Australian Broadcasting Corporation