Long-Term NSAID Use Linked to Reduced Dementia Risk, Study Finds

A 14.5-year study of nearly 12,000 adults suggests prolonged anti-inflammatory medication use may lower dementia risk by 12%.

Researchers tracked 11,745 adults over 14.5 years, finding a 12% lower dementia risk among long-term NSAID users.
Short- and intermediate-term NSAID use showed no significant protective effects against dementia.
The study found that the total cumulative dose of NSAIDs was not linked to dementia risk reduction.
Findings suggest prolonged, rather than intensive, anti-inflammatory effects may play a role in dementia prevention.
Experts caution against recommending long-term NSAID use for dementia prevention due to potential risks, including bleeding complications.