Memory Loss from Repeated Head Impacts Could Be Reversible, Study Suggests

Researchers are exploring non-invasive techniques to reactivate memory-forming neurons and potentially recover cognitive function in humans.

Researchers at Georgetown University Medical Center and Trinity College Dublin have found that memory loss due to repeated head impacts, such as those experienced by athletes, could potentially be reversed.
The study revealed that the memory loss is not a permanent event driven by a neurodegenerative disease, but rather due to inadequate reactivation of neurons involved in forming memories.
The researchers were able to reverse the amnesia in mice by using lasers to activate the 'memory engram' cells, but note that this invasive technique is not applicable to humans.
The team is now studying non-invasive techniques to communicate to the brain that it is no longer in danger and to open a window of plasticity that can reset the brain to its former state.
The study's findings could potentially lead to treatments to recover cognitive function in humans that have poor memory caused by repeated head impacts.