MIT Study Unveils Dual Effects of Fasting on Gut Health

Research in mice shows fasting boosts intestinal regeneration but increases cancer risk during refeeding.

Intestinal stem cells regenerate more effectively after fasting when refeeding begins.
The mTOR pathway is activated during refeeding, promoting cell growth and protein synthesis.
Increased stem cell activity during refeeding can lead to early-stage intestinal tumors in mice.
The study highlights the need for cautious dietary strategies to balance regeneration and cancer risk.
Further research is required to understand the implications for human health.