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Netflix Doc Revisits 1982 Tylenol Murders through Prime Suspect’s Final Interview

Featuring James Lewis’s only on-camera interview before his 2023 death, the series calls for fresh scrutiny of the unsolved poisonings.

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Overview

  • Cold Case: The Tylenol Murders premiered on Netflix May 26, 2025, using interviews and archive footage to re-examine the cyanide-laced capsule killings.
  • The three-part series includes James Lewis’s sole full interview—his last before dying in 2023—where he again denies involvement in the poisonings.
  • Filmmakers explore alternate contamination theories, including possible tampering at a Johnson & Johnson production facility and a 1986 Yonkers death.
  • The original 1982 attacks killed seven Chicago-area residents and spurred tamper-evident packaging requirements and federal product-tampering laws.
  • Directors hope the documentary prompts authorities to unseal records, broaden the suspect pool and uncover any additional victims.