Neuroscientists Unveil Mechanism Behind Brain's Detection of Surprises

Research reveals how the neocortex and thalamus amplify unexpected sensory input, offering insights into learning and brain disorders.

The neocortex and thalamus collaborate to generate prediction error signals by amplifying unexpected sensory input.
This process is crucial for learning and adapting to new information.
The study used advanced techniques like two-photon calcium imaging and optogenetics.
Findings could enhance understanding of brain circuit alterations in autism and schizophrenia.
Researchers employed a virtual reality environment to control and study sensory input in mice.