New Alzheimer’s Research Identifies Oligodendrocytes as Key Players in Disease Progression

Study finds that suppressing amyloid beta production in these brain cells can restore neuronal function, offering a potential new therapeutic approach.

Oligodendrocytes, not just neurons, produce amyloid beta, a protein linked to Alzheimer's disease.
Suppressing amyloid beta in oligodendrocytes improved brain pathology and neuronal function in mice.
The findings challenge the belief that neurons are the primary source of toxic amyloid beta.
Targeting oligodendrocyte-derived amyloid beta could become a novel treatment strategy for Alzheimer's.
The study highlights the importance of re-evaluating current Alzheimer's treatment approaches.