New Brain Pathway Discovery Offers Hope for Migraine Relief

Researchers identify cerebrospinal fluid's role in triggering migraines, revealing potential new drug targets.

Scientists found that cerebrospinal fluid (CSF) carries pain-triggering molecules to the trigeminal ganglion, a key nerve cluster.
The research shows CSF flows directly to the trigeminal ganglion, bypassing the blood-brain barrier.
This pathway explains the connection between migraine aura and the subsequent headache.
The study identifies specific proteins in CSF that activate sensory nerves, offering new targets for migraine therapies.
Findings could lead to better treatments for patients unresponsive to current migraine medications.