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New COVID Variant NB.1.8.1 Monitored in U.S. After Driving Surges in Asia

The variant, dominant in China and linked to rising cases in Taiwan and Hong Kong, has been detected in U.S. travelers without signs of widespread domestic transmission.

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Overview

  • NB.1.8.1, a SARS-CoV-2 variant driving surges in China, Hong Kong, and Taiwan, has been detected in travelers arriving at U.S. airports from nine countries.
  • State health authorities in Ohio, Rhode Island, and Hawaii have reported cases of NB.1.8.1 dating back to late March and early April, separate from airport screenings.
  • Preliminary research suggests the variant is not more immune-evasive but may be more transmissible due to stronger cell-binding capabilities.
  • Hong Kong and Taiwan are responding to rising severe cases and hospitalizations by urging mask use and stockpiling medical resources.
  • The FDA is deliberating updates to fall/winter COVID-19 vaccines, potentially targeting related JN.1 descendants like LP.8.1, which may cross-neutralize NB.1.8.1.