New Study Unveils Key Mechanism in Celiac Disease Immune Response

Researchers identify the role of intestinal epithelial cells in triggering gluten-related inflammation, paving the way for potential new treatments.

The study reveals that epithelial cells in the upper intestine actively contribute to the immune response against gluten.
This finding challenges the previous belief that only immune cells were involved in the inflammatory process.
Researchers used a biologically functioning model of the intestinal epithelium to isolate and observe specific molecular reactions.
The presence of pathogens like Pseudomonas aeruginosa can amplify the immune response to gluten.
The discovery may lead to new drug targets and treatment options for celiac disease patients.