Overview

• Red yeast rice contains monacolin K, a compound chemically identical to the statin drug lovastatin, which inhibits cholesterol production in the liver.
• A Belgian study reported a 22% reduction in LDL cholesterol over eight weeks with red yeast rice extract, while a University of Pennsylvania study found a 42% drop when combined with fish oil.
• The efficacy of red yeast rice supplements varies widely due to differences in monacolin K content and product quality, raising concerns about standardization.
• Experts recommend consulting a healthcare professional before using red yeast rice, particularly for individuals on other medications or with pre-existing conditions.
• Dietary and lifestyle changes, such as increased exercise and a healthy diet, remain foundational for managing cholesterol, with statins prescribed when these measures are insufficient.