Scientists Map 50,000 DNA 'Knots' with Potential Links to Disease

New research identifies i-motifs in key genomic areas, opening avenues for innovative treatments and diagnostics.

Researchers at the Garvan Institute mapped over 50,000 i-motifs in the human genome.
These structures, once controversial, are now recognized as widespread and significant in gene regulation.
I-motifs are linked with highly active genes and cancer-related oncogenes like MYC.
Potential therapies could target i-motifs to influence gene expression and treat hard-to-cure cancers.
The study demonstrates the power of advanced antibody tools in genomic research.