Overview

• Researchers observed oral microbiota convergence among newlywed couples over six months, correlating with shared increases in depression, anxiety, and sleep disturbances.
• The study highlighted significant microbial changes in healthy spouses married to partners with depression-anxiety (DA) phenotypes, aligning with altered salivary cortisol levels.
• Specific bacterial taxa, including Clostridia and Veillonella, were more prevalent in individuals with DA phenotypes, suggesting potential microbial markers for mental health.
• Women experienced more pronounced microbiome shifts and mental health effects, underscoring possible gender differences in susceptibility.
• While the findings are associational, researchers emphasize the need for longitudinal and interventional studies to explore causal links and therapeutic applications.