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Study Reveals Broad Benefits and Risks of GLP-1 Weight-Loss Drugs

New research highlights potential advantages for cognitive and cardiovascular health but warns of serious side effects like pancreatitis and kidney issues.

  • A comprehensive study of nearly 2 million patients found GLP-1 drugs reduce risks for 42 health conditions, including Alzheimer's, addiction, and cardiovascular issues.
  • The drugs, initially developed for diabetes, are now widely used for weight loss, with 1 in 8 Americans reporting past or current use.
  • Key benefits include reduced inflammation in the brain, improved impulse control, and lower risks of suicidal ideation and substance use disorders.
  • Serious side effects identified include gastrointestinal issues, kidney stones, drug-induced pancreatitis, and low blood pressure, requiring careful patient monitoring.
  • Researchers emphasize the need for long-term studies to evaluate risks, benefits, and effectiveness of newer GLP-1 formulations.
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