Synthetic Genes Pave Way for Precision-Controlled Biomolecular Materials
Researchers have developed synthetic gene cascades that can precisely time the assembly and disassembly of DNA-based structures, offering new possibilities in synthetic biology.
- The study, conducted by UCLA and the University of Rome Tor Vergata, demonstrates how synthetic genes can mimic natural gene cascades to control the timing of molecular assembly.
- These artificial genes can build and disassemble structures using DNA tiles, similar to how cells develop tissues through molecular signals.
- The research utilizes RNA molecules to trigger the formation or dissolution of nanoscale DNA structures at specific times.
- This approach allows for the creation of diverse materials from a limited set of components by adjusting the timing of gene activation.
- The findings open up potential applications in medicine and biotechnology, supported by various international research grants.
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ScienceDaily 