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Tufts Researchers Advance Saliva-Sensing Floss for Real-Time Stress Monitoring

The innovative dental floss, designed to detect cortisol levels, is being commercialized for routine health tracking and expanded biomarker applications.

Cropped shot of a young couple flossing their teeth together
The saliva is picked up by capillary action through a very narrow channel in the floss. Credit: Neuroscience News

Overview

  • Tufts University engineers, led by Professor Sameer Sonkusale, have developed a floss-based biosensor that measures cortisol in saliva for real-time stress monitoring.
  • The device integrates microfluidics and electropolymerized molecularly imprinted polymers (eMIPs) to enable precise, non-invasive cortisol detection during daily flossing routines.
  • Lab tests have demonstrated the sensor's accuracy is comparable to leading cortisol detection devices, as documented in a peer-reviewed study published in ACS Applied Materials & Interfaces.
  • Researchers are forming a startup to commercialize the floss sensor, with plans to adapt the technology for tracking additional salivary biomarkers like glucose, estrogen, and cancer markers.
  • While not intended for initial clinical diagnoses, the floss sensor is positioned as a tool for ongoing health monitoring, offering potential for personalized wellness management.