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US and Iran Express Cautious Optimism After Inconclusive Fifth Round of Talks

Iran’s refusal to suspend uranium enrichment at Rome negotiations left a key impasse ahead of a UN watchdog review.

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A general view shows the reactor at the nuclear power plant in Bushehr, 1200 kilometers (746 miles) south of Tehran February 25, 2009. Iran said on Wednesday it had carried out successful tests at its Russian-built Bushehr nuclear power plant in a step towards its launch. REUTERS/Caren Firouz (IRAN)
President Donald Trump speaks to reporters before boarding Air Force One at Morristown Municipal Airport in Morristown, N.J., Sunday, May 25, 2025.

Overview

  • The fifth round of Oman-mediated talks in Rome on May 23 ended with negotiators calling progress positive but leaving major issues unresolved.
  • President Trump praised “very, very good” discussions and suggested an announcement on a breakthrough could come within days.
  • Iran’s foreign ministry reiterated that enrichment remains non-negotiable and rejected any proposal for a temporary freeze.
  • US envoy Steve Witkoff reaffirmed that Washington demands a full halt to Iran’s enrichment to prevent weaponization.
  • Negotiators await details for a sixth round as both sides prepare for a June International Atomic Energy Agency review and the October expiry of the 2015 accord.