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U.S. Drug Overdoses Stabilize Around 109,000 Deaths After Two Years of Sharp Increases But Crisis Continues

  • Overdose deaths in the U.S. plateaued around 109,000 in 2022, indicating the crisis may have peaked but the death toll remains unacceptably high.
  • Fentanyl and other synthetic opioids continue to drive the majority of overdose deaths, while deaths linked to cocaine and methamphetamines also rose slightly.
  • Eight states reported over 100 fewer overdose deaths in 2022 compared to 2021, citing expanded treatment, naloxone distribution and other initiatives.
  • Experts remain unsure if the deadliest drug overdose epidemic in U.S. history has peaked or will surge again.
  • The Biden administration has increased efforts to curb overdoses but the crisis continues to significantly impact life expectancy and public health.
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