Vagus Nerve Stimulation Shows Promise for Severe Depression Treatment

A clinical trial involving nearly 500 participants reveals significant improvements in symptoms, though high costs limit accessibility.

Researchers tested vagus nerve stimulation (VNS) therapy in a year-long trial with 493 participants suffering from treatment-resistant depression.
Participants implanted with an activated device reported measurable improvements in depressive symptoms, quality of life, and daily functioning.
The therapy involves a pacemaker-like device sending electrical pulses to areas of the brain associated with mood regulation via the left vagus nerve.
Despite promising results, the high cost of the device and surgery remains a significant barrier, as most insurance plans currently do not cover it.
The study aims to provide data to convince Medicare and private insurers to cover the therapy, potentially expanding its availability.