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Vitamin D3 Shown to Slow Biological Aging by Preserving Telomere Length

A VITAL trial sub-study reveals that daily 2,000 IU vitamin D3 supplementation over four years reduces telomere shortening, equivalent to nearly three years of delayed aging.

New research found that vitamin D supplements may play a role in slowing the biological aging process.
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Overview

  • The VITAL trial sub-study, involving 1,054 adults aged 50 and older, found that daily vitamin D3 supplementation slowed telomere shortening over four years.
  • Participants taking 2,000 IU of vitamin D3 daily experienced a reduction in telomere attrition equivalent to nearly three years of delayed biological aging compared to a placebo group.
  • Telomeres are protective DNA caps that shorten with age, and their attrition is linked to diseases like cancer, heart disease, and dementia.
  • Omega-3 fatty acid supplementation showed no significant effect on telomere length, highlighting vitamin D3's specific role in telomere preservation.
  • Researchers recommend further studies to confirm long-term clinical benefits and refine supplementation guidelines, emphasizing targeted rather than universal use.