Drug Resistance Transmission Epidemiology Severe Malaria Symptoms Outbreaks Artemisinin Resistance Mortality Rates Global Malaria Situation Hemorrhagic Fever Respiratory Infections Pathogen Resistance Malaria Control Treatment Malaria-protective Mutation Malaria Prevention Malaria in Africa Global Efforts Impact on Vulnerable Populations Barriers to Accessing Services Malaria Vaccine Development Plasmodium berghei Prevention and Control Prevention South Sudan