Robert Downey Jr. Jonathan Majors Anthony Mackie Chris Evans Hugh Jackman Harrison Ford Ryan Reynolds Tom Holland Don Cheadle Dafne Keen John Malkovich Kit Harington Wesley Snipes Mark Ruffalo Chris Pratt Chris Hemsworth Tim Blake Nelson Simu Liu Colman Domingo Henry Cavill Florence Pugh Cast Changes Tobey Maguire Gwyneth Paltrow Sebastian Stan Channing Tatum Jeremy Renner Nicolas Cage Marisa Tomei Tenoch Huerta Kelsey Grammer David Harbour Frank Grillo Jeff Bridges Multiple Roles Benedict Cumberbatch Faran Tahir Joseph Quinn