Shannen Doherty Christina Applegate Ayo Edebiri Cheryl Hines Nominees Lead Actresses Alyssa Milano Michelle Trachtenberg Holly Marie Combs Chanel Maya Banks Emma Roberts Jenna Fischer Lead Actress Betty White Quinta Brunson Multiple Sclerosis Linda Lavin Julia Louis-Dreyfus Gena Rowlands Danielle Fishel Melissa Gilbert Natalie Morales Reese Witherspoon Ashley Tisdale Sandra Oh Ali Bastian Lucy Hale Elizabeth Debicki Anna Sawai Carrie Coon Imelda Staunton Jennifer Aniston Achievements Career Challenges Rupali Ganguly Hayden Panettiere Trina McGee The Rookie Dame Maggie Smith Maggie Smith Mahima Chaudhry Career Media Coverage Rachel Bilson Bethany Joy Lenz Sarah Drew Sydney Sweeney One Tree Hill Child Stars Nia Sharma Personal Stories Chrissy Metz Olivia Munn Jennifer Love Hewitt Madison De La Garza Teri Garr Sophie Turner Game of Thrones Mayfair Witches Saskia Fischer Chanel Banks Niki Aneja Walia Natalie Wood Emmy Award Winners Allison Mack Julie Stevens Hina Khan Jill Jacobson Diane Delano Olivia Hussey Karen Gillan Stella Stevens Parks and Recreation Jessica Gunning Muskan Nancy James Roopal Tyagi Joan Plowright Public Perception Lili Reinhart Jan Shepard South African Actresses Karla Sofía Gascón Surbhi Chandna Urvashi Dholakia Alice Hirson Career Highlights Health Advocacy Pamela Bach Emily Osment Pamela Bach Hasselhoff Rose McGowan Diane Lane Calista Flockhart Riley Keough Camila Morrone Comedy Series Supporting Actresses Winners Jennifer Coolidge Sabrina Impacciatore